{
    "id": 8519,
    "date": "2023-02-21T10:19:02",
    "date_gmt": "2023-02-21T08:19:02",
    "guid": {
        "rendered": "https:\/\/www.alivitpharm.com\/?page_id=8519"
    },
    "modified": "2023-02-21T11:16:38",
    "modified_gmt": "2023-02-21T09:16:38",
    "slug": "alpha-lipoic-acid",
    "status": "publish",
    "type": "page",
    "link": "https:\/\/www.alivitpharm.com\/en\/alpha-lipoic-acid\/",
    "title": {
        "rendered": "Alpha-Lipoic Acid"
    },
    "content": {
        "rendered": "<div data-elementor-type=\"wp-page\" data-elementor-id=\"8519\" class=\"elementor elementor-8519\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-55eb493 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"55eb493\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0e99a3d\" data-id=\"0e99a3d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-25a630f elementor-widget elementor-widget-heading\" data-id=\"25a630f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Alpha-Lipoic Acid<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea32578 elementor-widget elementor-widget-image\" data-id=\"ea32578\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.alivitpharm.com\/wp-content\/uploads\/2022\/10\/pill.png\" title=\"pill\" alt=\"Pill\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5dc68f2 elementor-widget elementor-widget-text-editor\" data-id=\"5dc68f2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>Thioctic Acid<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-77db749 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"77db749\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0066087\" data-id=\"0066087\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e741d72 elementor-widget elementor-widget-text-editor\" data-id=\"e741d72\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Alpha-lipoic acid<\/strong> is a substance that is used as a prevention or aid in the treatment of many chronic diseases that are associated with oxidative stress (such as diabetic neuropathy) and thus slows down the onset of metabolic syndrome, because it is considered a strong antioxidant.<\/p><p><strong><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Action mechanism:<\/span><\/span><\/strong>\u00a0<span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">There are two forms of alpha-lipoic acid: oxidized lipoic acid and reduced dehydro lipoic acid.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Both forms are capable of neutralizing free radicals, and their importance is reflected in the fact that neither form can be converted into a free radical.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Then, this substance has the ability to regenerate other antioxidants in our body, such as vitamins C and E, and also has a significant role in the synthesis of glutathione. <\/span><\/span><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">In the pathogenesis of inflammatory conditions, alpha-lipoic acid is very important because it exhibits an anti-inflammatory effect by inhibiting the synthesis of inflammatory factors, inhibiting the formation of inflammatory cytokines.<\/span><\/span> \u00a0<span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">The use of this substance is justified in the treatment of neuropathies that are a complication of type I and type II diabetes.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Many studies have concluded that a dose of alpha-lipoic acid of 300mg for 3 months maintains and improves vision in people suffering from both type I and type II diabetes.<\/span><\/span><\/p><p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Alpha-lipoic acid is available in the form of oral pharmaceutical forms, as well as in the form of intravenous injections.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0019cec elementor-widget elementor-widget-image\" data-id=\"0019cec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.alivitpharm.com\/wp-content\/uploads\/2022\/09\/leaves.png\" title=\"leaves\" alt=\"Leaves\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f2546df elementor-widget elementor-widget-text-editor\" data-id=\"f2546df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Alzheimer&#8217;s disease is a neurodegenerative disorder characterized by a decrease in cognitive functions related to orientation and memory, as well as a disorder of motor functions.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">This pathology is the result of abnormal deposition of beta-amyloid peptide.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Mitochondrial dysfunction plays a key role in the pathogenesis of Alzheimer&#8217;s disease.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Therefore, alpha-lipoic acid is a compound that has been well studied and is used as an adjunct in the treatment of many neurodegenerative diseases, including Alzheimer&#8217;s, due to its antioxidant, anti-inflammatory and neuroprotective potential.<\/span><\/span><\/p><p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Regarding the pharmacokinetic profile, alpha-lipoic acid has rapid absorption, low bioavailability, crosses the blood-brain barrier and is metabolized in the liver.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">It is very rare for this substance to interact with other supplements or drugs (so far no interactions have been clinically proven), so the use of alpha-lipoic acid is considered safe with pharmacotherapy.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Alpha-lipoic acid is considered a safe supplement, without any pronounced side effects.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">There is very little data on the use of this substance in the pediatric population, during pregnancy and breastfeeding, so you should consult your doctor or pharmacist about its use.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-96c5a0c elementor-widget elementor-widget-heading\" data-id=\"96c5a0c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">References<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b4afd7a elementor-widget elementor-widget-text-editor\" data-id=\"b4afd7a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31885820\/\" target=\"_blank\" rel=\"noopener\">Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer&#8217;s Disease?<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34450170\/\" target=\"_blank\" rel=\"noopener\">Decrypting the potential role of \u03b1-lipoic acid in Alzheimer&#8217;s disease<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33401674\/\" target=\"_blank\" rel=\"noopener\">Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and \u03b1-Lipoic Acid<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35445914\/\" target=\"_blank\" rel=\"noopener\">\u03b1-Lipoic Acid, an Organosulfur Biomolecule a Novel Therapeutic Agent for Neurodegenerative Disorders: An Mechanistic Perspective<\/a><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>",
        "protected": false
    },
    "excerpt": {
        "rendered": "<p>Alpha-Lipoic Acid Thioctic Acid Alpha-lipoic acid is a substance that is used as a prevention or aid in the treatment of many chronic diseases that are associated with oxidative stress (such as diabetic neuropathy) and thus slows down the onset of metabolic syndrome, because it is considered a strong antioxidant. Action mechanism:\u00a0There are two forms &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/www.alivitpharm.com\/en\/alpha-lipoic-acid\/\"> <span class=\"screen-reader-text\">Alpha-Lipoic Acid<\/span> Read More &raquo;<\/a><\/p>",
        "protected": false
    },
    "author": 9,
    "featured_media": 0,
    "parent": 0,
    "menu_order": 0,
    "comment_status": "closed",
    "ping_status": "closed",
    "template": "",
    "meta": {
        "site-sidebar-layout": "no-sidebar",
        "site-content-layout": "page-builder",
        "ast-global-header-display": "",
        "ast-main-header-display": "",
        "ast-hfb-above-header-display": "",
        "ast-hfb-below-header-display": "",
        "ast-hfb-mobile-header-display": "",
        "site-post-title": "disabled",
        "ast-breadcrumbs-content": "",
        "ast-featured-img": "disabled",
        "footer-sml-layout": "",
        "theme-transparent-header-meta": "",
        "adv-header-id-meta": "",
        "stick-header-meta": "",
        "header-above-stick-meta": "",
        "header-main-stick-meta": "",
        "header-below-stick-meta": "",
        "footnotes": ""
    },
    "class_list": [
        "post-8519",
        "page",
        "type-page",
        "status-publish",
        "hentry"
    ],
    "_links": {
        "self": [
            {
                "href": "https:\/\/www.alivitpharm.com\/en\/wp-json\/wp\/v2\/pages\/8519",
                "targetHints": {
                    "allow": [
                        "GET"
                    ]
                }
            }
        ],
        "collection": [
            {
                "href": "https:\/\/www.alivitpharm.com\/en\/wp-json\/wp\/v2\/pages"
            }
        ],
        "about": [
            {
                "href": "https:\/\/www.alivitpharm.com\/en\/wp-json\/wp\/v2\/types\/page"
            }
        ],
        "author": [
            {
                "embeddable": true,
                "href": "https:\/\/www.alivitpharm.com\/en\/wp-json\/wp\/v2\/users\/9"
            }
        ],
        "replies": [
            {
                "embeddable": true,
                "href": "https:\/\/www.alivitpharm.com\/en\/wp-json\/wp\/v2\/comments?post=8519"
            }
        ],
        "version-history": [
            {
                "count": 0,
                "href": "https:\/\/www.alivitpharm.com\/en\/wp-json\/wp\/v2\/pages\/8519\/revisions"
            }
        ],
        "wp:attachment": [
            {
                "href": "https:\/\/www.alivitpharm.com\/en\/wp-json\/wp\/v2\/media?parent=8519"
            }
        ],
        "curies": [
            {
                "name": "wp",
                "href": "https:\/\/api.w.org\/{rel}",
                "templated": true
            }
        ]
    }
}