{"id":14463,"date":"2026-06-02T13:50:25","date_gmt":"2026-06-02T11:50:25","guid":{"rendered":"https:\/\/www.alivitpharm.com\/?page_id=14463"},"modified":"2026-06-03T09:59:11","modified_gmt":"2026-06-03T07:59:11","slug":"epigallocatechin-gallate","status":"publish","type":"page","link":"https:\/\/www.alivitpharm.com\/fr\/epigallocatechin-gallate\/","title":{"rendered":"Gallate d\u2019\u00e9pigallocat\u00e9chine"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"14463\" class=\"elementor elementor-14463\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fe54679 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fe54679\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c5bdc82\" data-id=\"c5bdc82\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-06293a7 elementor-widget elementor-widget-heading\" data-id=\"06293a7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Gallate d\u2019\u00e9pigallocat\u00e9chine<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-51058fd elementor-widget elementor-widget-image\" data-id=\"51058fd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.alivitpharm.com\/wp-content\/uploads\/2022\/10\/pill.png\" title=\"pill\" alt=\"Pill\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f4557e elementor-widget elementor-widget-text-editor\" data-id=\"4f4557e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>\u00c9pigallocat\u00e9chine-3-gallate<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9d98309 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9d98309\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0404c90\" data-id=\"0404c90\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f315389 elementor-widget elementor-widget-text-editor\" data-id=\"f315389\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\"><strong>L'\u00e9pigallocat\u00e9chine gallate (EGCG)<\/strong> est la principale cat\u00e9chine du th\u00e9 vert. Elle poss\u00e8de des propri\u00e9t\u00e9s antioxydantes et un potentiel chimiopr\u00e9ventif (pr\u00e9vention du d\u00e9veloppement de cancers).<\/span><\/span><\/p><p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\"><strong> Qu'est-ce que l'EGCG?<\/strong>\u00a0L'EGCG est la principale cat\u00e9chine pr\u00e9sente dans le th\u00e9 vert <em>(Camellia sinensis)<\/em>.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Les polyph\u00e9nols (flavono\u00efdes) du th\u00e9 vert, dont l'EGCG, ont une activit\u00e9 antioxydante, r\u00e9duisent les dommages oxydatifs \u00e0 l'ADN et inhibent la formation de substances canc\u00e9rig\u00e8nes (par exemple, les nitrosamines).<\/span><\/span><\/p><p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\"><strong>Effets m\u00e9taboliques et glyc\u00e9miques:<\/strong> Une revue syst\u00e9matique\/m\u00e9ta-analyse de 2025 portant sur 41 essais contr\u00f4l\u00e9s randomis\u00e9s a montr\u00e9 qu'une suppl\u00e9mentation en EGCG entra\u00eenait de l\u00e9g\u00e8res r\u00e9ductions de la glyc\u00e9mie \u00e0 jeun et de l'HbA1c. <\/span><\/span><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">L'effet sur l'insulin\u00e9mie \u00e0 jeun n'\u00e9tait pas significatif et l'am\u00e9lioration globale du contr\u00f4le glyc\u00e9mique a \u00e9t\u00e9 jug\u00e9e peu susceptible d'avoir une pertinence clinique en tant qu'intervention unique pour la plupart des populations.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0b3bb1b elementor-widget elementor-widget-image\" data-id=\"0b3bb1b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/www.alivitpharm.com\/wp-content\/uploads\/2022\/09\/leaves.png\" title=\"leaves\" alt=\"Leaves\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad0bc95 elementor-widget elementor-widget-text-editor\" data-id=\"ad0bc95\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\"><strong>Donn\u00e9es en oncologie et radioprotection:<\/strong> Le th\u00e9 vert \/ EGCG est \u00e9tudi\u00e9 pour la pr\u00e9vention du cancer, avec un b\u00e9n\u00e9fice potentiel dans la pr\u00e9vention de certains types de cancers (vessie, \u0153sophage, pancr\u00e9as).<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Un vaste essai contr\u00f4l\u00e9 randomis\u00e9 portant sur un extrait de th\u00e9 vert standardis\u00e9 \u00e0 150 mg d\u2019EGCG deux fois par jour pendant 3 ans chez 879 patients ayant des ant\u00e9c\u00e9dents d\u2019ad\u00e9nomes colorectaux a montr\u00e9 une r\u00e9duction non significative de la r\u00e9cidive des ad\u00e9nomes.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Dans un mod\u00e8le murin et chez une cohorte de patients sous radioth\u00e9rapie, la prophylaxie orale par EGCG a r\u00e9duit les l\u00e9sions intestinales radio-induites associ\u00e9es \u00e0 une modulation du microbiote intestinal.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Dans une \u00e9tude en double aveugle sur la radioth\u00e9rapie mammaire postop\u00e9ratoire, l\u2019application topique d\u2019une solution d\u2019EGCG sur le champ d\u2019irradiation a r\u00e9duit la radiodermite et diminu\u00e9 l\u2019indice de sympt\u00f4mes.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Les effets ind\u00e9sirables li\u00e9s au traitement se sont limit\u00e9s \u00e0 des picotements et des d\u00e9mangeaisons.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">Les pr\u00e9parations \u00e0 base de th\u00e9 vert sont promues pour la pr\u00e9vention du cancer, l\u2019am\u00e9lioration des fonctions cognitives, la pr\u00e9vention des maladies cardiaques, la pr\u00e9vention de la maladie de Parkinson, l\u2019hypercholest\u00e9rol\u00e9mie, la perte de poids et d\u2019autres affections;<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">globalement, l'efficacit\u00e9 est jug\u00e9e \u00ab potentiellement efficace \u00bb pour les usages mentionn\u00e9s.<\/span><\/span><\/p><p><span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\"><strong>Effets ind\u00e9sirables et pr\u00e9cautions d'emploi:<\/strong> La plupart des donn\u00e9es de s\u00e9curit\u00e9 proviennent de produits \u00e0 base de th\u00e9 vert (contenant de l'EGCG, de la caf\u00e9ine et d'autres ingr\u00e9dients). Les effets ind\u00e9sirables rapport\u00e9s incluent, entre autres : agitation, anxi\u00e9t\u00e9, arythmies, insomnie, palpitations, tachycardie, troubles gastro-intestinaux, h\u00e9patotoxicit\u00e9, hypertension, hyperglyc\u00e9mie, hypercholest\u00e9rol\u00e9mie, tremblements et d\u00e9pendance\/syndrome de sevrage.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">La prudence est de mise chez les patients souffrant de troubles anxieux, de maladies cardiaques\/arythmies, de d\u00e9pression, de diab\u00e8te, d'hypertension, d'insuffisance r\u00e9nale ou d'ulc\u00e8re gastroduod\u00e9nal.<\/span><\/span> <span class=\"jCAhz ChMk0b\"><span class=\"ryNqvb\">L'utilisation de produits \u00e0 base de th\u00e9 vert est d\u00e9conseill\u00e9e pendant la grossesse et l'allaitement en raison du manque de donn\u00e9es.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f0fa3d1 elementor-widget elementor-widget-heading\" data-id=\"f0fa3d1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">R\u00e9f\u00e9rences<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-528cc14 elementor-widget elementor-widget-text-editor\" data-id=\"528cc14\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<ul><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40885603\/\" target=\"_blank\" rel=\"noopener\">Effect of Epigallocatechin Gallate on Glycemic Index: A Systematic Review and Meta-Analysis of Randomized Controlled Trials<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35213393\/\" target=\"_blank\" rel=\"noopener\">Green Tea Extract to Prevent Colorectal Adenomas, Results of a Randomized, Placebo-Controlled Clinical Trial<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39486483\/\" target=\"_blank\" rel=\"noopener\">EGCG protects intestines of mice and pelvic cancer patients against radiation injury via the gut microbiota\/D-tagatose\/AMPK axis<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35648426\/\" target=\"_blank\" rel=\"noopener\">Efficacy of Epigallocatechin-3-Gallate in Preventing Dermatitis in Patients With Breast Cancer Receiving Postoperative Radiotherapy: A Double-Blind, Placebo-Controlled, Phase 2 Randomized Clinical Trial<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/reference.medscape.com\/drug\/camellia-sinensis-camellia-thea-green-tea-344486#4\" target=\"_blank\" rel=\"noopener\">Green Tea (Camellia Sinensis, Camellia Thea, Chinese Tea Green Tea In Combination) &#8211; Adverse Effects<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/reference.medscape.com\/drug\/camellia-sinensis-camellia-thea-green-tea-344486#10\" target=\"_blank\" rel=\"noopener\">Green Tea (Camellia Sinensis, Camellia Thea, Chinese Tea Green Tea In Combination) &#8211; Pharmacology<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/reference.medscape.com\/drug\/camellia-sinensis-camellia-thea-green-tea-344486#2\" target=\"_blank\" rel=\"noopener\">Green Tea (Camellia Sinensis, Camellia Thea, Chinese Tea Green Tea In Combination) &#8211; Suggested Uses<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/reference.medscape.com\/drug\/camellia-sinensis-camellia-thea-green-tea-344486?_gl=1*1gfrlj9*_gcl_au*MTI2MjgxNTQ1OS4xNzc2MTg4MjEx#5\" target=\"_blank\" rel=\"noopener\">Green Tea (Camellia Sinensis, Camellia Thea, Chinese Tea Green Tea In Combination) &#8211; Warnings<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/reference.medscape.com\/drug\/camellia-sinensis-camellia-thea-green-tea-344486#6\" target=\"_blank\" rel=\"noopener\">Green Tea (Camellia Sinensis, Camellia Thea, Chinese Tea Green Tea In Combination) &#8211; Pregnancy &amp; Lactation<\/a><\/li><li><a class=\"reference-link\" href=\"https:\/\/reference.medscape.com\/drug\/camellia-sinensis-camellia-thea-green-tea-344486#0\" target=\"_blank\" rel=\"noopener\">Green Tea (Camellia Sinensis, Camellia Thea, Chinese Tea Green Tea In Combination) &#8211; Suggested Dosing<\/a><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Epigallocatechin Gallate Epigallocatechin-3-Gallate Epigallocatechin gallate (EGCG) is the main catechin in green tea with antioxidant and potential chemopreventive properties (prevents the development of malignant diseases). What is EGCG?\u00a0EGCG is the main catechin found in green tea (Camellia sinensis). Green tea polyphenols (flavonoids), including EGCG, have antioxidant activity, reduce oxidative DNA damage, and inhibit the formation &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/www.alivitpharm.com\/fr\/epigallocatechin-gallate\/\"> <span class=\"screen-reader-text\">Gallate d\u2019\u00e9pigallocat\u00e9chine<\/span> Lire la suite\u00a0\u00bb<\/a><\/p>","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-global-header-display":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","footnotes":""},"class_list":["post-14463","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/pages\/14463","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/comments?post=14463"}],"version-history":[{"count":17,"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/pages\/14463\/revisions"}],"predecessor-version":[{"id":14486,"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/pages\/14463\/revisions\/14486"}],"wp:attachment":[{"href":"https:\/\/www.alivitpharm.com\/fr\/wp-json\/wp\/v2\/media?parent=14463"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}